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Thierry Brue Selected Research

Hypopituitarism (Sheehan's Syndrome)

1/2021High-throughput splicing assays identify missense and silent splice-disruptive POU1F1 variants underlying pituitary hormone deficiency.
1/2020Hypopituitarism in Patients with Blepharophimosis and FOXL2 Mutations.
6/2017Lessons from monogenic causes of growth hormone deficiency.
12/2016Long-term outcome of macroprolactinomas.
10/2013Delayed diagnosis of Sheehan's syndrome in a developed country: a retrospective cohort study.
4/2012Genetic causes of combined pituitary hormone deficiencies in humans.
9/2011Detection of genetic hypopituitarism in an adult population of idiopathic pituitary insufficiency patients with growth hormone deficiency.
4/2010Role of stereotactic radiosurgery in the management of pituitary adenomas.
1/2009Radiotherapy and radiosurgery in acromegaly.
11/2008Congenital pituitary hormone deficiencies: role of LHX3/LHX4 genes.
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Thierry Brue Research Topics

Disease

31Acromegaly
06/2022 - 08/2005
26Neoplasms (Cancer)
02/2022 - 05/2007
23Pituitary Neoplasms (Pituitary Adenoma)
08/2022 - 07/2003
14Pituitary ACTH Hypersecretion
07/2021 - 12/2004
11Prolactinoma (Prolactinomas)
08/2022 - 05/2007
11Hypopituitarism (Sheehan's Syndrome)
01/2021 - 03/2004
11Adenoma (Adenomas)
06/2018 - 02/2002
10Cushing Syndrome
06/2022 - 01/2010
8Combined Pituitary Hormone Deficiency
11/2021 - 08/2005
7Adrenal Insufficiency (Adrenal Gland Hypofunction)
07/2021 - 11/2004
6Growth Hormone-Secreting Pituitary Adenoma
11/2021 - 09/2007
5Hypertension (High Blood Pressure)
06/2018 - 10/2010
4Hypothyroidism
01/2021 - 08/2005
4Hypokalemia
06/2018 - 01/2010
3Hyperplasia
12/2021 - 02/2016
3Cardiovascular Diseases (Cardiovascular Disease)
09/2021 - 06/2012
3Neuroendocrine Tumors (Neuroendocrine Tumor)
02/2020 - 10/2014
3Primitive Neuroectodermal Tumors (PNET)
02/2020 - 10/2014
3Perinatal Death
01/2011 - 11/2004
3ACTH-Secreting Pituitary Adenoma
09/2010 - 07/2003
3Carcinogenesis
09/2010 - 05/2007
2Type 2 Diabetes Mellitus (MODY)
09/2021 - 01/2020
2Obesity
09/2021 - 06/2012
2Metabolic Syndrome (Dysmetabolic Syndrome X)
09/2021 - 06/2012
2Hypophysitis
09/2019 - 02/2015
2Necrosis
01/2015 - 01/2009
2Common Variable Immunodeficiency
12/2014 - 01/2012
2Rare Diseases (Rare Disease)
06/2012 - 04/2012
2Infections
01/2012 - 12/2008
2Hypoglycemia (Reactive Hypoglycemia)
01/2012 - 01/2011
1Infertility (Sterility)
06/2022
1Diabetes Insipidus
02/2022
1Cysts
02/2022
1Hypoparathyroidism
01/2022
1Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
01/2022
1Hypercalciuria
01/2022
1Insulin Resistance
09/2021
1Dyslipidemias (Dyslipidemia)
09/2021

Drug/Important Bio-Agent (IBA)

17ProlactinIBA
08/2022 - 07/2003
16Adrenocorticotropic Hormone (ACTH)FDA Link
12/2021 - 03/2005
14Growth Hormone (Somatotropin)IBA
11/2021 - 12/2008
14Hormones (Hormone)IBA
01/2020 - 03/2004
13pegvisomantFDA LinkGeneric
06/2022 - 01/2009
11Hydrocortisone (Cortisol)FDA LinkGeneric
06/2022 - 09/2009
11Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
06/2021 - 12/2008
10Insulin-Like Growth Factor I (IGF-1)IBA
06/2022 - 09/2009
9Transcription Factors (Transcription Factor)IBA
01/2019 - 03/2004
8Dopamine Agonists (Dopamine Agonist)IBA
02/2021 - 04/2010
8Octreotide (Sandostatin)FDA LinkGeneric
06/2020 - 09/2007
7GlucocorticoidsIBA
04/2022 - 11/2004
6Pharmaceutical PreparationsIBA
12/2014 - 01/2009
5pasireotideIBA
06/2020 - 10/2014
5Proteins (Proteins, Gene)FDA Link
06/2012 - 10/2006
4Glucose (Dextrose)FDA LinkGeneric
02/2020 - 07/2016
4Temozolomide (Temodar)FDA LinkGeneric
01/2019 - 10/2010
4Messenger RNA (mRNA)IBA
01/2016 - 07/2003
4Biological ProductsIBA
04/2015 - 02/2002
3CabergolineFDA LinkGeneric
02/2021 - 11/2012
3Somatostatin Receptors (Somatostatin Receptor)IBA
01/2021 - 12/2008
3lanreotide (Somatuline)FDA Link
06/2020 - 11/2014
3Biomarkers (Surrogate Marker)IBA
09/2019 - 07/2016
3Dexamethasone (Maxidex)FDA LinkGeneric
08/2015 - 06/2009
3Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric
08/2015 - 12/2004
3aryl hydrocarbon receptor-interacting proteinIBA
10/2011 - 05/2007
2Gonadotropin-Releasing Hormone (GnRH)FDA Link
06/2022 - 01/2016
2Vasopressins (Vasopressin)IBA
02/2022 - 12/2004
2Ketoconazole (Nizoral)FDA LinkGeneric
12/2021 - 05/2014
2OsilodrostatIBA
12/2021 - 07/2021
2Protein Isoforms (Isoforms)IBA
11/2021 - 01/2021
2Insulin (Novolin)FDA Link
09/2021 - 01/2020
2Triglycerides (Triacylglycerol)IBA
09/2021 - 12/2017
2Dopamine (Intropin)FDA LinkGeneric
06/2021 - 01/2012
2Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
01/2021 - 01/2017
2LigandsIBA
01/2021 - 01/2020
2fluorodopa F 18IBA
02/2020 - 02/2018
2Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
07/2019 - 06/2018
2SteroidsIBA
06/2018 - 05/2014
2Chromogranin AIBA
02/2018 - 10/2014
2N 30IBA
04/2016 - 07/2010
2GonadotropinsIBA
12/2012 - 07/2003
2Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
08/2012 - 01/2010
2Mifepristone (RU 486)FDA Link
08/2012 - 01/2010
2Alkylating AgentsIBA
06/2012 - 06/2012
2Pro-Opiomelanocortin (Proopiomelanocortin)IBA
10/2006 - 07/2003
1AndrogensIBA
06/2022
1Metoclopramide (Reglan)FDA LinkGeneric
01/2022
1Vitamin DFDA LinkGeneric
01/2022
1Teriparatide (Parathar)FDA Link
01/2022
1CalciumIBA
01/2022
1Lipoproteins (Lipoprotein)IBA
09/2021
1Apolipoprotein C-IIIIBA
09/2021
1Cytidine Triphosphate (CTP)IBA
03/2021

Therapy/Procedure

26Therapeutics
02/2022 - 02/2002
11Radiotherapy
08/2021 - 08/2005
7Adrenalectomy
03/2021 - 06/2012
2Thyroidectomy
01/2022 - 01/2019
2Immunomodulation
09/2019 - 02/2015
2Drug Therapy (Chemotherapy)
06/2012 - 06/2012
1Contraception (Birth Control)
06/2022
1Operative Surgical Procedures
02/2022